Automated detection of progressive speech changes in early Alzheimer's disease.

Jessica Robin,Mengdan Xu,Aparna Balagopalan,Jekaterina Novikova, Laura Kahn,Abdi Oday,Mohsen Hejrati,Somaye Hashemifar,Mohammadreza Negahdar,William Simpson,Edmond Teng

Alzheimer's & dementia (Amsterdam, Netherlands)（2023）

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摘要

Longitudinal speech samples were analyzed to characterize speech changes in early AD.Acoustic and linguistic measures showed significant change over 18 months.A novel speech composite score was computed to characterize longitudinal change.The speech composite correlated with primary and secondary trial endpoints.Automated speech analysis could facilitate remote, high frequency monitoring in AD.

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关键词

progressive speech changes,early alzheimer,automated detection

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