In vivo activity of the dual SYK/FLT3 inhibitor TAK-659 against pediatric acute lymphoblastic leukemia xenografts.

Pediatric blood & cancer（2023）

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摘要

TAK-659 exhibited low to moderate single-agent in vivo activity against pediatric ALL PDXs representative of diverse subtypes.

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关键词

lymphoblastic leukemia,inhibitor,dual syk/flt3

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