Prognostic value of tumor necrosis based on the evaluation of frequency in invasive breast cancer.

BMC cancer(2023)

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摘要
TN-score was an independent prognostic factor for 5-year DFS. Only high-risk TN was associated with poor prognosis. High-risk TN "up-staged" the patients with IBC. Incorporating TN-score into staging category could improve its performance to stratify patients.
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关键词
Frequency,Invasive breast cancer,Multiphoton imaging,Tumor necrosis,Spatial heterogeneity,Prognosis
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