Disturbed microbiota-metabolites-immune interaction network is associated with olfactory dysfunction in patients with chronic rhinosinusitis.

Xingyu Han,Xuejia He,Xiaojun Zhan,Linyin Yao,Zhifu Sun,Xing Gao,Shan Wang,Zhenlin Wang

Frontiers in immunology（2023）

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摘要

The disturbed nasal microbiota-metabolite-immune interaction networks may be implicated in the pathogenesis of OD in CRS patients and the underlying pathophysiological mechanisms need to be further investigated in future studies.

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关键词

olfactory dysfunction, inflammatory cytokines, type 1, type 2 immune response, chronic rhinosinusitis, metagenomics, metabolomics

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