The prognostic impact of reduced variant burden in elderly patients with acute myeloid leukemia treated with decitabine.

Mihee Kim,TaeHyung Kim,Seo-Yeon Ahn,Jun Hyung Lee,Ju Heon Park,Myung-Geun Shin,Sung-Hoon Jung,Ga-Young Song,Deok-Hwan Yang,Je-Jung Lee,Seung Hyun Choi,Mi Yeon Kim,Jae-Sook Ahn,Hyeoung-Joon Kim,Dennis Dong Hwan Kim

The Korean journal of internal medicine（2023）

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摘要

This study suggested that combining ΔVAF ≥ 58.6%, a molecular response, with morphologic and hematologic responses can more accurately predict OS in elderly AML patients after decitabine therapy.

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关键词

Acute myeloid leukemia, Elderly patients, Decitabine, Allele frequency, Residual neoplasm

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