TrkA inhibition alleviates bladder overactivity in cyclophosphamide-induced cystitis by targeting hyperpolarization-activated cyclic nucleotide-gated channels.

Iranian journal of basic medical sciences(2023)

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摘要
Our results suggested that increased TrkA expression during chronic cystitis promotes the development of bladder overactivity by targeting the HCN channels.
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关键词
Cyclophosphamide, Cystitis, activated-cyclic nucleotide, gated channels, kinase A, Urinary bladder, Hyperpolarization
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