Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy.

Ni Wang,Junyan Yang,Ruijun Chen,Yunyun Liu,Shunjie Liu,Yining Pan,Qingfeng Lei,Yuzhou Wang,Lu He,Youqiang Song,Zhong Li

Journal of ginseng research（2023）

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摘要

Our studies demonstrate the neuroprotective mechanism of ginsenoside Rg1 in AD models. Rg1 induces PINK-Parkin mediated mitophagy and ameliorates memory deficits in 5XFAD mouse models.

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关键词

Alzheimer's disease, ginseng, ginsenoside Rg1, mitophagy, Parkin

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