Immune checkpoint inhibition in advanced colorectal cancer with inherited and acquired microsatellite instability: Current state and future directions.

Constantin A Dasanu, Mohammed Alani, Shaghayegh Habibi, Ion Codreanu

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners（2023）

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摘要

Overall, the outlook in advanced colorectal cancer patients with MSI appears optimistic as new and efficacious ICI drugs and combinations are being added to the existing therapeutic armamentarium.

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关键词

Immune checkpoint inhibitor, deficient mismatch repair, microsatellite instability, tumor mutational burden, colorectal cancer

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