Long non-coding RNA DINO promotes cisplatin sensitivity in lung adenocarcinoma via the p53-Bax axis.

Zhile Liu,Qi Wang, Yue Bi,Alexey S Chubarov,Ying Li,Lu Liu,Xia Yang,Elena V Dmitrienko,Yanfang Zheng

Journal of thoracic disease（2023）

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摘要

The lncRNA regulates the sensitivity of lung adenocarcinoma to cisplatin by stabilizing and activating the axis, and thus, may be a novel therapeutic target to overcome cisplatin resistance.

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关键词

Lung adenocarcinoma (LUAD), long noncoding RNA DINO, p53, cisplatin resistance

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