Humoral Immunity After COVID-19 Vaccination in Chronic Lymphocytic Leukemia and Other Indolent Lymphomas: A Single-Center Observational Study.

Peter G Doukas,Frederique St Pierre,Reem Karmali,Xinlei Mi,Jennifer Boyer,Mariana Nieves,Michael G Ison,Jane N Winter,Leo I Gordon,Shuo Ma

The oncologist（2023）

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摘要

Antibody response is lower in patients with indolent lymphomas compared to the general population. Lower Ab seropositivity was found in patients with a history of anti-leukemic agent therapy or those immunized with Pfizer vaccine. This data suggests that Moderna vaccination may confer a greater degree of immunity against SARS-CoV-2 in patients with indolent lymphomas.

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Non-Hodgkin's lymphomas, chronic lymphocytic leukemia, COVID-19, vaccination, rituximab, BTK inhibitors

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