ID: 197424 Improvement in Quality-of-Life and Motor Function: Real-World, Prospective Study of Directional DBS Systems

Early Deep Brain Stimulation (DBS) systems used ring-shaped electrodes to achieve axial selectivity in stimulation of target tissue. However, directional current steering allows for rotational selectivity (in addition to axial) and has the potential to further improve patient outcomes by avoiding off-target stimulation due to the ability to create a well-defined field around the intended target. Several pilot studies have corroborated the use of directionality and its impact on therapeutic window and adverse effects.1-3 In this report, real-world outcomes using Directional DBS Systems with multiple independent current source control (MIC() for use in managing symptoms of levodopa responsive Parkinson's disease (PD) are reported.