Personalized estimates of morphometric similarity in multiple sclerosis and neuromyelitis optica spectrum disorders
NeuroImage: Clinical(2023)
摘要
•PBSI shows quantifiable brain structural heterogeneity correlations in MS and NMOSD.•Six multi-center datasets validation for PBSI measurements at group level.•MS showed a greater neuroanatomical heterogeneity pattern than NMOSD.•MS and NMOSD exhibit different brain regions that may drive disease heterogeneity.•MS and NMOSD show age stage-dependency of neuroanatomical heterogeneity.
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