Association of serum homocysteine, folate, and vitamin B12 and mood following the Swank and Wahls elimination dietary interventions in relapsing-remitting multiple sclerosis: Secondary analysis of the WAVES trial

Farnoosh Shemirani,Tyler J. Titcomb,Solange M. Saxby,Patrick Ten Eyck,Linda M. Rubenstein,Karin F. Hoth,Linda G. Snetselaar,Terry L. Wahls

Multiple Sclerosis and Related Disorders（2023）

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摘要

•Both diets had significant improvements in anxiety and depression scores.•Serum levels of homocysteine were reduced, and folate and vitamin B12 increased.•No association of depressive symptoms changes with serum homocysteine or vitamin B12.

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关键词

Multiple sclerosis, Low-saturated fat diet, Modified Paleolithic elimination diet, Depression, Homocysteine, VitaminB12

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