ADSCs increase the autophagy of chondrocytes through decreasing miR-7-5p in Osteoarthritis rats by targeting ATG4A

Shu Zhao,Yu'e Liu,Jian Wang,Yi Wen,Baitong Wu,Danjing Yang,Guangming Wang,Guanghui Xiu,Bin Ling,Dajiang Du,Jun Xu

International Immunopharmacology（2023）

引用 0|浏览5

暂无评分

摘要

•The ADSCs treatment repaired the articular cartilage and maintained chondrocytes ECM homeostasis through modulating chondrocytes autophagy in OA.•This is the first report that ADSCs promoted cartilage repair through inhibiting the expression of miR-7-5p in OA.•ATG4A was defined as a target gene of miR-7-5p.•The ADSCs treatment repaired the articular cartilage through the mTORC1 signaling pathways in OA.

查看译文

关键词

Osteoarthritis,ADSCs,autophagy,miR-7-5p,cartilage repair

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要