Pediatric reference values of alkaline phosphatase: Analysis from a German population-based cohort and influence of anthropometric and blood parameters

•We established new reference values for alkaline phosphatase from healthy children.•AP strongly depends on sex and age especially, during infancy and adolescence.•Tanner stage and anthropometric parameters such as BMI were associated with AP.•Growth parameters such as growth velocity and height-SDS were associated with AP.•We found positive, sex-depending associations between AP and ALAT, ASAT and GGT.