CAREPATH methodology for development of computer interpretable, integrated clinical guidelines.

The process of developing a computer interpretable, integrated clinical guideline requires multiple considerations and decisions. As part of the CAREPATH project, a holistic approach to comorbidity has been adopted using an integrated clinical guideline for the management of multimorbid patients with mild cognitive impairment or mild dementia. The project’s clinical and technical teams would later interpret and implement the integrated clinical guideline into the CAREPATH holistic computer interpretable guideline. Three phases should be completed to accomplish the patient-centered computer interpretable guideline modelling, which include the conceptual modelling, interpretable modelling and localization phases, respectively. This paper describes the methodological viewpoints of this process and the relevant considerations.