Beyond being an energy supplier, ATP synthase is a sculptor of mitochondrial cristae

Héctor Miranda-Astudillo, Marcos Ostolga-Chavarría,Pierre Cardol,Diego González-Halphen

Biochimica et Biophysica Acta (BBA) - Bioenergetics（2022）

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摘要

Mitochondrial F1/FO ATP synthase participation in the mitochondrial permeability transition pore complex (PTPC) remains controversial. Neginskaya et al. (Cell Rep. 2019;26:11–17) reported an unexpected current with PTPC-like properties in F1/FO ATP synthase C subunit knockout cells that could explain part of the conflictual literature.

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关键词

atp synthase,energy supplier

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