Effectiveness of A Fourth Dose of COVID-19 mRNA Vaccine in the Elderly Population During the Omicron BA.2 and BA.5 Circulation: A Nationwide Cohort Study in Korea (K-COVE)

Seon Kyeong Park,Young June Choe,Eun Jung Jang,Ryu Kyung Kim,Do-Sang Lim,Seonju Yi,Sangwon Lee,Geun-Yong Kwon, Jee Yeon Shin,Sang-Yoon Choi,Mi Jin Jeong,Young-Joon Park

Open Forum Infectious Diseases（2023）

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摘要

AbstractWe estimate the effectiveness of a fourth dose booster of coronavirus disease 2019 mRNA vaccine in individuals aged ≥60 years during Omicron BA.2 and BA.5 circulation in Korea. The effectiveness against critical infection was 67.7% (95% confidence interval, 50.7%–78.8%) at 31–60 days and 62.1% (95% confidence interval, 45.5%–73.7%) at 61–90 days.

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elderly population,nationwide cohort study,cohort study,k-cove

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