687 right ventricular disfunction in a patient with cctga treated with arni

Abstract Congenitally Corrected Transposition of Great Arteries is a unique condition in which atrio-ventricular discrepancy e ventricular-arteriosus discrepancy are mutually balanced, so that there is the normal oxygenation and distribution of the blood to the tissues, but the morphologically right ventricle and the tricuspid valve have to deal with systemic pressures, developing severe ventricular disfunction and valve regurgitation along the years. We presented the case of a young male patient from India with Congenitally Corrected Transposition of Great Arteries, Ventricular Septum Defect and Pulmonary Artery Stenosis, for which he was treated surgically by positioning a valved conduit between the morphologically left ventricle and the pulmonary artery; he developed worsening dyspnoea years after the operation and further investigations in our centre demonstrated the patency of the conduit and right (systemic) ventricular disfunction that we decided, in a pioneering manner, to treat with Sacubitril/Valsartan.