Impact of Alcohol Consumption on Quality of Life, Depressive Mood and Metabolic Syndrome in Obstructive Lung Disease Patients: Analysis of Data from Korean National Health and Nutrition Examination Survey from 2014 and 2016

Background: The objective of this study was to investigate whether alcohol consump- tion might affect the quality of life (QOL), depressive mood, and metabolic syndrome in patients with obstructive lung disease (OLD).Methods: Data were obtained from the Korean National Health and Nutrition Examina-tion Survey from 2014 and 2016. OLD was defined as spirometry of forced expiratory volume in 1 second/forced vital capacity <0.7 in those aged more than 40 years. QOL was evaluated using the European Quality of Life Questionnaire-5D (EQ-5D) index. Patient Health Questionnaire-9 (PHQ-9) was used to assess the severity of depressive mood. Alcohol consumption was based on a history of alcohol ingestion during the pre-vious month.Results: A total of 984 participants with OLD (695 males, 289 females, age 65.8 +/- 9.7 years) were enrolled. The EQ-5D index was significantly higher in alcohol drinkers (n=525) than in non-alcohol drinkers (n=459) (0.94 +/- 0.11 vs. 0.91 +/- 0.13, p=0.002). PHQ-9 scores were considerably lower in alcohol drinkers than in non-alcohol drinkers (2.15 +/- 3. 57 vs. 2.78 +/- 4.13, p=0.013). However, multiple logistic regression analysis showed that alcohol consumption was not associated with EQ-5D index or PHQ-9 score. Body mass index >= 25 kg/m2, triglyceride >= 150 mg/dL, high-density lipoprotein <40 mg/dL in men and <50 mg/dL in women, and blood pressure >= 130/85 mm Hg were significantly more common in alcohol drinkers than in non-alcohol drinkers (all p<0.05).Conclusion: Alcohol consumption did not change the QOL or depressive mood of OLD patients. However, metabolic syndrome-related factors were more common in alcohol drinkers than in non-alcohol drinkers.