Supplementary Figures S1-S5 from Keratin-17 Promotes p27<sup>KIP1</sup> Nuclear Export and Degradation and Offers Potential Prognostic Utility

Endogenous expression of K17 in cervical cancer cell lines and knockdown efficiency by siRNAs and shRNAs against K17 in SiHa and CaSki cells (S1); K17 knockdown induces cell-cycle arrest at G1 (S2); K17 knockdown induces p27KIP1 nuclear accumulation (S3); p27KIP1-ubiquitin ligases expression is not altered by K17 knockdown (S4); K17 interacts with p27KIP1 in the nucleus (S5).