Shape design of an artificial pump-lung using high-resolution hemodynamic simulation with high-performance computing

Accurate and fast prediction of the hemodynamics of the artificial pump-lung is critical in the design process. In this study, a comprehensive computational framework, including a sliding mesh method, a coupled free flow and porous media flow model, a hemolysis prediction method, a k - ? shear stress transport turbulence model, and solution algorithms, is introduced to accurately predict the velocity field, pressure heads, and hemolysis. The framework is used to do the shape design of an artificial pump-lung on a supercomputer. High-resolution hemodynamics simulation results are obtained and analyzed, and the parallel performance of the algorithm is studied. The numerical results indicate that the proposed framework is capable of accurately predicting the velocity field, pressure heads, and hemolysis, and the performance of the designed artificial pump-lung meets the biocompatibility requirements. Additionally, the parallel performance results demonstrate the potential of the framework to efficiently perform the design of artificial pump-lungs using a large number of processors.