Factors Associated with Detection of Hereditary Diffuse Gastric Cancer on Endoscopy in Individuals with Germline CDH1 Mutations

Monika Laszkowska,Laura Tang,Elvira Vos,Stephanie King,Erin Salo-Mullen,Patrick T. Magahis,Miseker Abate,Amanda Catchings,Ann G. Zauber,Anne I. Hahn,Mark Schattner,Daniel Coit,Zsofia K. Stadler,Vivian E. Strong,Arnold J. Markowitz

Gastrointestinal Endoscopy（2023）

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摘要

Targeted biopsies of gastric pale mucosal areas and increasing number of biopsies taken on EGD were associated with detection of SRCC. SRCC foci were mostly detected in the proximal stomach, supporting updated endoscopic surveillance guidelines. Further studies are needed to refine endoscopic protocols to improve SRCC detection in this high-risk population.

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关键词

CDH1,endoscopy,hereditary diffuse gastric cancer,signet ring cell carcinoma

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