BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis.

Sumit Agarwal,Farrukh Afaq,Prachi Bajpai,Michael Behring,Hyung-Gyoon Kim,Amith Varambally,Darshan S Chandrashekar,Shajan Peter,Sameer Al Diffalha,Moh'd Khushman,Andreas Seeber,Sooryanarayana Varambally,Upender Manne

Molecular cancer research : MCR（2023）

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摘要

FDA-approved small-molecule inhibitors of EZH2 can indirectly target BZW2 and because BZW2 functions as an oncogene, these inhibitors could serve as therapeutic agents for colorectal cancer.

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关键词

bzw2 inhibition,colorectal cancer growth,colorectal cancer,metastasis

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