Alemtuzumab treatment exemplifies discordant immune effects of blood and cerebrospinal fluid in multiple sclerosis.

Louisa Müller-Miny,Michael Heming,Tobias Lautwein,Tobias Ruck,I-Na Lu,Heinz Wiendl,Gerd Meyer Zu Hörste

Journal of neuroimmunology（2023）

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摘要

The CSF and blood compartments are thus partially uncoupled, emphasizing that the CNS is only partially accessible even for treatments profoundly affecting the blood.

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关键词

Alemtuzumab,Multiple sclerosis,Single cell RNA sequencing

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