Regulation of the circadian clock in C. elegans by clock gene homologs kin-20 and lin-42.

Circadian rhythms are endogenous oscillations present in nearly all organisms from prokaryotes to humans, allowing them to adapt to cyclical environments close to 24 hours. Circadian rhythms are regulated by a central clock, which is based on a transcription-translation feedback loop. One important protein in the central loop in metazoan clocks is PERIOD, which is regulated in part by Casein kinase 1 ε/δε/δCaenorhabditis elegansperiodcasein kinase 1ε/δlin-42kin-20lin-42kin-20lin-42kin-20C. eleganssur-5