213. Epigenetic Markers of Lithium Use in Bipolar Disorder

Emese Kovács, Emma Simpson-Wade,Jenny Gringer Richards,Aislinn Williams,John Wemmie,Vincent Magnotta,Jess Fiedorowicz,Marie Gaine

Biological Psychiatry（2023）

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摘要

Lithium is a gold standard of maintenance treatment for bipolar disorder (BD) and has been recently studied for its neuroprotective action and anti-aging properties. The precise mechanism for these actions, however, is not well understood, though epigenetics may help to bridge this understanding.

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关键词

DNA methylation, Bipolar Disorder, Lithium, FSTL4, Epigenetics

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