Patterns of care and outcomes of risk reducing surgery in women with pathogenic variants in non-BRCA and Lynch syndrome ovarian cancer susceptibility genes.
Gynecologic oncology(2023)
摘要
No occult ovarian or tubal cancers were observed in either group. No recurrent or primary gynecologic-related cancers occurred upon follow-up. Despite frequent menopausal symptoms, HRT use was rare. Both groups experienced surgical complications when hysterectomy and/or concurrent colon surgery was performed suggesting concurrent surgeries should only be performed when indicated.
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关键词
BRIP1,Lynch,MLH1,MSH2,MSH6,Non-BRCA,RAD51C,RAD51D,Risk-reducing,Salpingo-oophorectomy
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