Lenvatinib Can Overcome Immune Resistance in Head and Neck Cancer and Achieve Durable Remission
SOUTH ASIAN JOURNAL OF CANCER(2023)
摘要
Squamous cell carcinoma head and neck is the sixth most common cancer worldwide and.[1] Multimodality therapies have been advocated for locoregional relapse or metastatic disease.[2] Combination therapy with lenvatinib has been considered to overcome resistance and improve the efficacy.[3] In a recent study of lenvatinib and pembrolizumab conducted in heavily pretreated recurrent and metastatic head and neck cancer, the median overall survival OS was 6.2 months, and the median progression-free survival (PFS) was 4.6 months.[4]
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关键词
neck cancer,lenvatinib,immune resistance
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