Supplementary Figure S3 from Metabolic Profiling of Formalin-Fixed Paraffin-Embedded Tissues Discriminates Normal Colon from Colorectal Cancer

Supplementary Figure S3. (A, B): Principal component (PC) analysis plot showing the distribution of the tumor and normal tissues in FFPE samples in the top two PC space before (A) and after (B) removal of 2 FFPE samples. (C, D): PC analysis plot showing the distribution of the tumor and normal tissues in fresh frozen samples in first and second PC (C) as well as first and third PC (D); whereby the analysis was conducted using the Spearman correlation between the tumor and normal samples on the 200 (A, B) and 536 (C, D) detected metabolites. FFPE, formalin-fixed paraffin-embedded; PC, principal component.