Supplementary Table 2 from Heterogeneity and Cancer-Related Features in Lymphangioleiomyomatosis Cells and Tissue

Table S2. A, Differentially expressed LAMp genes between non-LAM and LAM cells (FDR < 5%; Guo dataset). B, Differential gene expression between LAM cells with low and high LAMcore values (all genes considered). C, Curated gene sets positively correlated (FDR < 5%) with LAMcore in LAM cells. D, Curated gene sets negatively correlated (FDR < 5%) with LAMcore in LAM cells. E, Curated gene sets positively correlated (FDR < 5%) with LAMp in LAM cells. F, Curated gene sets negatively correlated (FDR < 5%) with LAMp in LAM cells. G, Overexpressed genes (n = 50) in depicted six cancer cell lines and LAM cells, relative to all other cancer cell lines analyzed. H, Overrepresented GO terms and KEGG pathways in the 50 genes commonly overexpressed in the six cancer cell lines and LAM cells. I, Overrepresented transcription factor binding sites in LAMp and LAMcore signatures. J, Overrepresented GO terms and KEGG pathways (FDR < 5%) in 10% of the most variably expressed genes among bulk LAM lung samples. K, Inferred immune cell contents in bulk LAM lung nodules (n = 14; GEO GSE12027) using CIBERSORTx.