Preclinical characterization and IND-enabling safety studies for PNT001, an antibody that recognizes cis-pT231 tau.
Alzheimer's & dementia : the journal of the Alzheimer's Association(2023)
摘要
The data support clinical development of PNT001 in human tauopathies.
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关键词
RT-QuIC,Tg4510 mouse,cis-pT231 tau,tau aggregation,tauopathy
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