Supplementary Figures 1 - 5 from CD95L Cell Surface Cleavage Triggers a Prometastatic Signaling Pathway in Triple-Negative Breast Cancer

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PDF file - 3848K, Figure S1. Pathological doses of cl-CD95L trigger cell migration of TNBC cells. Figure S2. Cl-CD95L induces migration of TNBC cells through a PI3K(p110β)/c-yesdriven signaling pathway. Figure S3. NOX-3-dependent ROS production is instrumental in CD95-mediated cell motility in TNBC cells. Figure S4. Cl-CD95L induces co-localization of CD95 with EGFR. Figure S5. cl-CD95L promotes migration of TNBC cells via EGFR-dependent and EGFindependent signaling pathways.

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