Implementation of dihydropyrimidine dehydrogenase deficiency testing in Europe

M. de With, A. Sadlon, E. Cecchin,V. Haufroid, F. Thomas, M. Joerger,R.H.N. van Schaik,R.H.J. Mathijssen,C.R. Largiadèr

ESMO Open（2023）

引用 32|浏览11

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摘要

The EMA recommendations have supported the implementation of DPD deficiency testing in Europe. Key factors for successful implementation were test reimbursement and clear clinical guidelines. Further efforts to improve the oncologists' awareness of the clinical relevance of DPD testing in clinical practice are needed.

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关键词

DPD deficiency,DPYD,fluoropyrimidine,implementation survey,pre-therapeutic testing,toxicity

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