Neuroprotective effect of angiotensin II receptor blockers on the risk of incident Alzheimer's disease: A nationwide population-based cohort study.
Frontiers in aging neuroscience（2023）
摘要
Long-term use of BBB-crossing ARBs significantly reduced the risk of AD development. The finding may provide valuable insight into disease-modifying drug options for preventing AD in patients with cardiovascular diseases.
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关键词
Alzheimer’s disease,angiotensin II receptor blocker,blood–brain barrier,neuroprotective agents,renin-angiotensin system
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