TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration.

Michael Karl Melzer,Silvia Schirge,Johann Gout,Frank Arnold,Dharini Srinivasan,Ingo Burtscher,Chantal Allgöwer,Medhanie Mulaw,Friedemann Zengerling,Cagatay Günes,Heiko Lickert,Vincent M Christoffels,Stefan Liebau,Martin Wagner,Thomas Seufferlein,Christian Bolenz,Anne M Moon,Lukas Perkhofer,Alexander Kleger

BMC biology（2023）

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摘要

TBX3 demonstrates dynamic expression patterns in the pancreas. Although TBX3 is dispensable for proper pancreatic development, its absence leads to altered organ regeneration after induction of acute pancreatitis.

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关键词

Acute pancreatitis,Embryonic development,Organ regeneration,Pancreatic development,TBX3

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