Clinical management of molecular alterations identified by high throughput sequencing in patients with advanced solid tumors in treatment failure: Real-world data from a French hospital.

Sandra Pinet,Stéphanie Durand, Alexandre Perani, Léa Darnaud, Fifame Amadjikpe, Mathieu Yon,Tiffany Darbas, Alain Vergnenegre,Thomas Egenod, Yannick Simonneau,Valérie Le Brun-Ly, Julia Pestre,Laurence Venat, Frédéric Thuillier,Alain Chaunavel,Mathilde Duchesne, Véronique Fermeaux,Anne Guyot, Sylvain Lacorre,Barbara Bessette,Fabrice Lalloué,Karine Durand,Elise Deluche

Frontiers in oncology（2023）

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摘要

This study highlights that an organized center with a Multidisciplinary Molecular Tumor Board and an NGS screening system can obtain satisfactory results comparable with those of large centers for including patients in clinical trials.

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FoundationOne CDx,cancer,liquid biopsy,next-generation sequencing,precision oncology,targeted therapy

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