Airway hyperresponsiveness reflects corticosteroid-sensitive mast cell involvement across asthma phenotypes.

Morten Hvidtfeldt,Asger Sverrild,Alexis Pulga,Laurits Frøssing,Alexander Silberbrandt,Morten Hostrup,Martin Thomassen,Caroline Sanden,Carl Magnus Clausson,Premkumar Siddhuraj,Daisy Bornesund,Juan Jose Nieto-Fontarigo,Lena Uller,Jonas Erjefält,Celeste Porsbjerg

The Journal of allergy and clinical immunology（2023）

引用 2|浏览20

暂无评分

摘要

Airway hyperresponsiveness to mannitol is related to mast cell infiltration across asthma phenotypes, correlating with epithelial mast cells in patients with Feno-high asthma and with airway smooth muscle mast cells in patients with Feno-low asthma. Treatment with inhaled corticosteroids was effective in reducing airway hyperresponsiveness in both groups.

查看译文

关键词

Asthma,airway hyperresponsiveness,inhaled corticosteroids,mast cell

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要