Accurate diagnosis of prostate cancer by combining Proclarix with magnetic resonance imaging.
BJU international(2023)
摘要
When combined with mpMRI and prostate volume, Proclarix reliably predicted csPCa and ruled out men with no or indolent cancer. A large reduction of two thirds of unneeded biopsies was achieved. Proclarix can further be used with high confidence to reliably detect csPCa in men with an indeterminate PI-RADS score 3 mpMRI. Despite these encouraging results, further validation is needed.
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关键词
PSA,Proclarix,Proclarix-MRI score,biomarkers,biopsy,cathepsin D,diagnosis,mpMRI,prostate cancer,thrombospondin-1
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