Post hoc longitudinal assessment of the efficacy and safety of recombinant factor IX Fc fusion protein in hemophilia B

Amy D. Shapiro,Roshni Kulkarni,Margaret V. Ragni,Hervé Chambost,Johnny Mahlangu,Johannes Oldenburg,Beatrice Nolan,Margareth C. Ozelo,Meredith C. Foster,Annemieke Willemze,Christopher Barnowski,Nisha Jain,Bent Winding,Jennifer Dumont,Stefan Lethagen,Chris Barnes,K. John Pasi

Blood advances（2023）

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摘要

•Pooled longitudinal efficacy and safety data for rFIXFc demonstrates sustained benefits in hemophilia B.•All evaluable target joints resolved during treatment, and no recurrence was reported in most (90%) baseline target joints during follow-up.

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