Minimal Residual Disease Detection Using Gene Scanning Analysis, Fluorescent Fragment Analysis, and Capillary Electrophoresis for IgH Rearrangement in Adult B-Lineage Acute Lymphoblastic Leukemia: A Cross-Sectional Study.

Sepideh Shahkarami,Samareh Younesian,Shahrbano Rostami,Farzad Kompani,Davood Bashash,Seyed Asadollah Mousavi,Seyed H Ghaffari

Cell journal（2023）

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摘要

It seems that the PCR-based GeneScan analysis of IGH gene rearrangement detection may be a valuable molecular technique to distinguish monoclonality from polyclonality. And also, it may be a precise tool to detect the residual leukemic DNA in the PB follow-up samples of patients.

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关键词

Acute lymphoblastic leukemia,Capillary Gel Electrophoresis,GeneScanning,Immunoglobulin Heavy Chain,Minimal Residual Disease

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