High Macrophage Densities in Native Kidney Biopsies Correlate With Renal Dysfunction and Promote ESRD

Maren B Pfenning,Jessica Schmitz,Irina Scheffner,Kevin Schulte,Abedalrazag Khalifa,Hossein Tezval,Alexander Weidemann,Anke Kulschewski,Ulrich Kunzendorf,Sebastian Dietrich,Hermann Haller,Jan T Kielstein,Wilfried Gwinner,Jan H Bräsen

Kidney International Reports（2023）

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摘要

Precise quantification of macrophage densities in renal biopsies may contribute to risk stratification to identify patients with high risk for end-stage renal disease (ESRD) and might be a promising therapeutic target in renal disease.

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关键词

Dialysis risk,Digital pathology,Disease progression,Macrophage,Native kidney disease,Renal pathology

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