Single antiplatelet therapy directly after percutaneous coronary intervention in non-ST-segment elevation acute coronary syndrome patients: the OPTICA study.

Niels M R van der Sangen,Bimmer E P M Claessen,I Tarik Küçük,Alexander W den Hartog,Jan Baan,Marcel A M Beijk,Ronak Delewi,Tim P van de Hoef,Paul Knaapen,Jorrit S Lemkes,Koen M Marques,Alexander Nap,Niels J W Verouden,M Marije Vis,Robbert J de Winter,Wouter J Kikkert,Yolande Appelman,Jose P S Henriques

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology（2023）

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摘要

This study provides first-in-human evidence that P2Y inhibitor monotherapy directly following PCI for NSTE-ACS is feasible, without any overt safety concerns, and highlights the need for randomised controlled trials comparing direct P2Y inhibitor monotherapy with the current standard of care.

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关键词

ACS/NSTE-ACS, adjunctive pharmacotherapy, bleeding, myocardial infarction, stent thrombosis

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