Short-term exposure to fine particulate matter and genome-wide DNA methylation in chronic obstructive pulmonary disease: A panel study conducted in Beijing, China.

Ruirui Duan,Hongtao Niu,Fen Dong,Tao Yu,Xuexin Li,Hanna Wu,Yushi Zhang, Ting Yang

Frontiers in public health（2022）

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摘要

This study provided evidence for a significant relationship between personal PM exposure and DNA methylation in patients with COPD. Our research also revealed a new biological pathway explaining the adverse effects of PM exposure on COPD risk.

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关键词

DNA-methylation,PM2.5,chronic obstructive pulmonary disease (COPD),health effect,inflammation

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