Dynamics of high hydrostatic pressure resistance development in RpoS-deficient Escherichia coli

Elisa Gayán,Zhiying Wang,Maika Salvador,Michael G. Gänzle,Abram Aertsen

Food Research International（2023）

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摘要

•RpoS attenuated E. coli can develop HHP resistance via cyaA/crp or tnaA mutations.•Both mutants co-emerge because of different growth vs tolerance characteristics.•Mutations in yegW led to HHP resistance independent of RpoS, cAMP/CRP or TnaA.

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关键词

Escherichia coli,Resistance development,High hydrostatic pressure,Heat resistance,cAMP/CRP regulation,Tryptophanase,YegW regulator,RNA pyrophosphohydrolase

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