Variations in dynamic tumor-associated antigen-specific T cell responses correlate with HCC recurrence after thermal ablation.

Chaoran Zang,Yan Zhao,Guihai Liu,Kang Li,Ling Qin,Yuewei Zhang,Jianping Sun,Qi Wang,Liang Ma,Peng Zhao,Yu Sun,Dandan Guo,Chunwang Yuan,Tao Dong,Yonghong Zhang

Frontiers in immunology（2022）

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摘要

Ablation elicits a transient antitumor immune response in patients with HCC by changing the profile of the T cell response and the expression of immune checkpoint molecules, which correlated with longer recurrence-free survival of patients with HCC.

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关键词

T-cell immune response,ablation,hepatocellular carcinoma,recurrence,tumor-associated antigen

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