JUND facilitates proliferation and angiogenesis of esophageal squamous cell carcinoma cell via MAPRE2 up-regulation

Tissue and Cell(2023)

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摘要
•MAPRE2 and JUND are highly expressed in ESCC cell lines.•MAPRE2 down-regulation suppresses cell proliferation and angiogenesis in ESCC.•JUND facilitates the transcription of MAPRE2.•JUND down-regulation curbs cell proliferation and angiogenesis in ESCC.•JUND promoted cell proliferation and angiogenesis in ESCC via MAPRE2.
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关键词
Esophageal squamous cell carcinoma,JUND,MAPRE2,Proliferation,Angiogenesis,Transcription factor
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