Pyruvate dehydrogenase B regulates myogenic differentiation via the FoxP1-Arih2 axis.

Xuan Jiang,Siyu Ji, Fenglai Yuan,Tushuai Li,Siyuan Cui,Wei Wang,Xianlong Ye,Rong Wang,Yongquan Chen,Shenglong Zhu

Journal of cachexia, sarcopenia and muscle（2022）

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摘要

The comprehensive results show that PDHB plays a sarcoprotective role by suppressing the FoxP1-Arih2 axis and may serve as a therapeutic target in sarcopenia.

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关键词

PDHB,ageing,myogenesis,sarcopenia

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