Chemokine receptor 7 mediates miRNA-182 to regulate cerebral ischemia/reperfusion injury in rats.

Qi Wang, Sifan Xu,Bin Wang,Yu Qin,Yachen Ji,Qian Yang,Yang Xu,Zhiming Zhou

CNS neuroscience & therapeutics（2023）

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摘要

CXCR7 protects against cerebral I/R injury, possibly via the miR-182/TCF7L2/Hippo pathway. These results indicate that CXCR7 affects cerebral ischemia-reperfusion injury through miRNA regulation and downstream pathways.

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关键词

cerebral ischemia/reperfusion injury,chemokine receptor 7,hippo pathway,microRNA

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