Development of gamma delta T cells in the thymus - A human perspective

gamma delta T cells are increasingly emerging as crucial immune regulators that can take on innate and adaptive roles in the defence against pathogens. Although they arise within the thymus from the same hematopoietic precursors as conventional alpha beta T cells, the development of gamma delta T cells is less well understood. In this review, we focus on summarising the current state of knowledge about the cellular and molecular processes involved in the gener-ation of gamma delta T cells in human.